Zebrafish regenerate full thickness optic nerve myelin after demyelination, but this fails with increasing age
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چکیده
منابع مشابه
Zebrafish regenerate full thickness optic nerve myelin after demyelination, but this fails with increasing age
INTRODUCTION In the human demyelinating central nervous system (CNS) disease multiple sclerosis, remyelination promotes recovery and limits neurodegeneration, but this is inefficient and always ultimately fails. Furthermore, these regenerated myelin sheaths are thinner and shorter than the original, leaving the underlying axons potentially vulnerable. In rodent models, CNS remyelination is more...
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Stem cells are undifferentiated cells that have the ability to convert to different types of cells and after dividing, they can produce their own cells or other cells. Axons of the retinal ganglion cells, from the optic nerve. These cells lose the ability to regenerate themselves before birth. Optic nerve degeneration can result from various causes including increased intraocular pressure, comp...
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Raman, NMR and EPR spectroscopy and electrophysiology methods were used to investigate the excitability and the packaging of myelin lipid layers and its viscosity during nerve exposure to pronase E. It was established that during exposure of nerve to pronase E the action potential (AP) conduction velocity and the Schwann cell (SC) (or myelin) water ordering increases, but the nerve myelin refra...
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ژورنال
عنوان ژورنال: Acta Neuropathologica Communications
سال: 2014
ISSN: 2051-5960
DOI: 10.1186/preaccept-5005406801297956